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GM-CSF engages multiple signaling pathways to enhance pro-inflammatory cytokine responses in human monocytes during <i>Legionella</i> infection

2024-12-10

Abstract excerpt

The proinflammatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) is required for host defense against a wide range of pathogens. We previously found that GM-CSF enhances inflammatory cytokine production in murine monocytes and is required for in vivo control of the intracellular bacterial pathogen Legionella pneumophila . It is unclear whether GM-CSF similarly augments cytokine production i...

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Literature Corpus work
972d5896-4bc4-56e0-8e34-5a3eb39ac752
DOI
10.1101/2024.12.05.627084
Open publication

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GM-CSF engages multiple signaling pathways to enhance pro-inflammatory cytokine responses in human monocytes during <i>Legionella</i> infectionDOI 10.1101/2024.12.05.627084
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