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Article

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

Journal of leukocyte biology - 1 Aug 2009

Fleetwood Andrew J, Dinh Hang, Cook Andrew D, Hertzog Paul J, Hamilton John A

Abstract excerpt

M-CSF and GM-CSF are mediators involved in regulating the numbers and function of macrophage lineage populations and have been shown to contribute to macrophage heterogeneity. Type I IFN is an important mediator produced by macrophages and can have profound regulatory effects on their properties. In this study, we compared bone marrow-derived macrophages (BMM) and GM-CSF-induced BMM (GM-BMM) from wild-type and...

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Source

Identifiers

PMID: 19406830
DOI: 10.1189/jlb.1108702

Genes

IFNAR1
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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