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Article

Evaluation of the effect of GM-CSF blocking on the phenotype and function of human monocytes.

Scientific reports - 31 Jan 2020

Lotfi Noushin, Zhang Guang-Xian, Esmaeil Nafiseh, Rostami Abdolmohamad

Abstract excerpt

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a multipotent cytokine that prompts the proliferation of bone marrow-derived macrophages and granulocytes. In addition to its effects as a growth factor, GM-CSF plays an important role in chronic inflammatory autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. Reports have identified monocytes as the primary target of GM-CSF;...

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Identifiers

PMID: 32005854
DOI: 10.1038/s41598-020-58131-2
PMCID: PMC6994676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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