Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluating the evidence for GM-CSF as a host-directed therapy in respiratory infections

24 Feb 2025

Abstract excerpt

Novel therapeutic approaches are needed to treat respiratory infections due to the rising antimicrobial resistance and the lack of effective antiviral therapies. A promising avenue to overcome treatment failure is to develop strategies that target the host immune response rather than the pathogen itself. Granulocyte-macrophage colony-stimulating factor (GM-CSF) plays a critical role in controlling homeostasis in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pediatric health and respiratory diseases
Share to Respiratory Support and Mechanisms
Share to Respiratory viral infections research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39999678
DOI: 10.1016/j.cyto.2025.156902

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluating the evidence for GM-CSF as a host-directed therapy in respiratory infectionsPMID 39999678Read ↗

Beneficial and Detrimental Effects of Cytokines during Influenza and COVID-19Semantic proximity Read ↗

GM-CSF engages multiple signaling pathways to enhance pro-inflammatory cytokine responses in human monocytes during <i>Legionella</i> infectionSemantic proximity Read ↗

Immune dysregulation in the pathogenesis of pulmonary alveolar proteinosis.Semantic proximity Read ↗

GM-CSF Grown Bone Marrow Derived Cells Are Composed of Phenotypically Different Dendritic Cells and Macrophages.Semantic proximity Read ↗

Infectious Chronic Rhinosinusitis.Semantic proximity Read ↗

Antibiotics as immunomodulators: a potential pharmacologic approach for ARDS treatment.Semantic proximity Read ↗

Induction and Regulation of Endogenous Granulocyte Colony-Stimulating Factor FormationSemantic proximity Read ↗

The role of IFN-γ/CXCL10 axis in Mycoplasma pneumonia infectionSemantic proximity Read ↗

Inflammation as a Modulator of Host Susceptibility to Pulmonary Influenza, Pneumococcal, and Co-InfectionsSemantic proximity Read ↗

Pulmonary macrophage transplantation therapy.Semantic proximity Read ↗

Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know.Semantic proximity Read ↗

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.