Article

GM-CSF and M-CSF Driven Differentiation Differentially Regulates Chikungunya Virus Infection and Antiviral Responses in Human Monocyte-Derived Macrophages

2026-03-12

Abstract excerpt

<h4>ABSTRACT</h4> Chikungunya virus is an arthritogenic alphavirus causing debilitating joint pain in infected individuals. The mechanisms driving CHIKV-associated arthralgia is poorly understood, however, macrophages have been implicated as potential reservoirs of persistent viral material and mediators of immunopathology. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) and Macrophage-Colony Stimulatin...

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Literature Corpus work: 707160b6-ba3a-5ad2-a188-177b09001210
DOI: 10.64898/2026.03.11.710213

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