Article

Transient and DNA-free <i>in vivo</i> CRISPR/Cas9 genome edition for flexible modelling of endometrial carcinogenesis

2022-06-17

Abstract excerpt

<h4>ABSTRACT</h4> The CRISPR/Cas9 technology has emerged as a powerful tool to generate mouse models of disease. Endometrial cancer is the most common malignancy of the female genital tract. In the present study, we have developed a pipeline for the generation of somatically engineered mouse models of endometrial cancer by in vivo electroporation-mediated delivery of Cas9 ribonucleoprotein into the uterine cavit...

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Literature Corpus work: 96c436ce-572d-5078-a191-390273199cc1
DOI: 10.1101/2022.06.17.496593

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