Article

Chimeric chromosome landscapes of human somatic cell cultures show dependence on stress and regulation of genomic repeats by CGGBP1

2021-10-30

Abstract excerpt

<h4>ABSTRACT</h4> Genomes of somatic cells in culture are prone to spontaneous mutations due to errors in replication and DNA repair. Some of these errors, such as chromosomal fusions, are not rectifiable and subject to selection or elimination in growing cultures. Somatic cell cultures are thus expected to generate background levels of potentially stable chromosomal chimeras. A description of the landscape of su...

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Literature Corpus work: 96b13b54-bf38-5062-9675-6cac4eaa910f
DOI: 10.1101/2021.10.30.466567

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