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Generation and characterization of a tamoxifen-inducible, Cre driver rat for transgene expression in microglia

2025-07-21

Abstract excerpt

Microglia are the resident immune cells of the central nervous system (CNS) and display diverse functions under both physiological and pathological conditions. The past decade has seen burgeoning interest in microglia function, with a variety of transgenic tools developed for specific genetic manipulation of microglia in various injury, disease, and developmental models. Although the majority of models have been d...

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Literature Corpus work
96a9cef6-6867-5fc9-9edb-7b4eef8cc73c
DOI
10.1101/2025.07.17.665447
Open publication

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Generation and characterization of a tamoxifen-inducible, Cre driver rat for transgene expression in microgliaDOI 10.1101/2025.07.17.665447
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