Article

Conditional Genetic Deletion of CSF1 Receptor in Microglia Ameliorates the Physiopathology of Alzheimer’s Disease

2020-10-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common form of dementia in the world. Microglia are the innate immune cells of CNS, their proliferation, activation and survival in pathologic and healthy brain have previously been shown to be highly dependent on CSF1R. <bold>Methods:</bold> Here we investigate the impact of such...

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Literature Corpus work: 46f00fa4-df41-516a-95f7-2aa56891bbf4
DOI: 10.21203/rs.3.rs-80698/v1

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