Article

Differential induction of interferon stimulated genes between type I andtype III interferons is independent of interferon receptor abundance

2018-10-19

Abstract excerpt

It is currently believed that type I and III interferons (IFNs) have redundant functions. However, the preferential distribution of type III IFN receptor on epithelial cells suggests functional differences at epithelial surfaces. Here, using human intestinal epithelial cells we could show that although both type I and type III IFNs confer an antiviral state to the cells, they do so with distinct kinetics. Type I I...

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Identifiers and source

Literature Corpus work: 969c3174-e64c-5414-a427-9fd31f5df8b9
DOI: 10.1101/448357

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