Article

Low basal expression and slow induction of IFITM3 puts immune cells at risk of influenza A infection

2019-12-23

Abstract excerpt

The interferon-induced transmembrane protein, IFITM3, has been shown to restrict influenza virus infection in murine and in vitro settings for ten years, but no explanation has been found to explain why this virus infection is so highly contagious and infects most individuals it comes in contact with. We confirm that the expression level of IFITM3 plays a role in determining the level of viral infection through m...

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Identifiers and source

Literature Corpus work: 1f8c7558-fe08-5e2d-b4ac-e8c655ad01db
DOI: 10.1101/2019.12.20.885590

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