Article

eQTLs identify regulatory networks and drivers of variation in the individual response to sepsis

2023-09-22

Abstract excerpt

Sepsis is a clinical syndrome of life-threatening organ dysfunction caused by a dysregulated response to infection, for which disease heterogeneity is a major obstacle to developing targeted treatments. We have previously identified gene expression-based patient subgroups (Sepsis Response Signatures: SRS) informative for outcome and underlying pathophysiology. Here we aimed to investigate the role of genetic varia...

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Literature Corpus work: 969bd5c3-276a-5b1e-9c94-45611a68d6dd
DOI: 10.1101/2023.09.22.558983

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