Article
Rare genetic variant risks in patients with sepsis-associated acute respiratory distress syndrome.
Respiratory research - 25 Feb 2026
Tosco-Herrera Eva, Rubio-Rodríguez Luis A, Muñoz-Barrera Adrián, Jáspez David, Suárez-Pajes Eva, Corrales Almudena, Alonso-González Aitana, Prieto-González Miryam, Rodríguez-Pérez Aurelio, Carriedo Demetrio, Blanco Jesús, Ambrós Alfonso, Lorente Leonardo, Martín María M, Solé-Violán Jordi, Rodríguez-Gallego Carlos, González-Higueras Elena, Espinosa Elena, Muriel-Bombin Arturo, Domínguez David, Soro Marina, Hernández-Beeftink Tamara, Añón José M, Villar Jesús, Guillén-Guio Beatriz, Marcelino-Rodríguez Itahisa, Lorenzo-Salazar José M, González-Montelongo Rafaela, Flores Carlos
Abstract excerpt
BACKGROUND: Acute respiratory distress syndrome (ARDS) is a complex, heterogeneous, and deadly condition often resulting from pulmonary lesions due to sepsis, among other causes. There is a lack of targeted therapies to specifically treat the patients. Common genetic factors in the population (frequency > 1%) have been associated with ARDS susceptibility, but systematic genetic screens of the role of rare genetic...
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