Article

An immune dysfunction score for stratification of patients with acute infection based on whole blood gene expression

2022-03-18

Abstract excerpt

Dysregulated host responses to infection can lead to organ dysfunction and sepsis, causing millions of deaths globally each year. To alleviate this burden, improved prognostication and biomarkers of response are urgently needed. We investigated the use of whole blood transcriptomics for stratification of patients with severe infection by integrating data from 3,149 samples of sepsis patients and healthy individual...

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Literature Corpus work: fb07111d-f5ea-571b-bdeb-e80b1276fcd3
DOI: 10.1101/2022.03.17.22272427

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