Article

Mapping and modeling human colorectal carcinoma interactions with the tumor microenvironment

2022-09-15

Abstract excerpt

<h4>Summary</h4> The initiation and progression of cancer are inextricably linked to the tumor microenvironment (TME). Understanding the function of specific cancer-TME interactions poses a major challenge due in part to the complexity of the in vivo microenvironment. Here we predict cancer-TME interactions from single cell transcriptomic maps of both human colorectal cancers (CRCs) and mouse CRC models, ask how...

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Literature Corpus work: 964944ab-2bb2-5583-9bd9-df4e643795f3
DOI: 10.1101/2022.09.13.506996

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