Article
Deciphering spatial heterogeneity of patient-derived organoids of colorectal tumors for drug discovery
2026-02-12
Abstract excerpt
The spatial organization of tumors is critical for drug development, as spatial heterogeneity in cancer cells and the tumor microenvironment can present a significant barrier to effective therapies. Patient-derived tumor organoids (PDOs) offer promising platforms to study tumor biology and for drug development. Previous studies have demonstrated that PDOs can maintain the genomic/clonal heterogeneity of tumors, as...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- b31e6850-64a3-5082-9dd8-91d709540f94
- DOI
- 10.64898/2026.02.10.704651