Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The NLRP3 rs10754558 polymorphism is a risk factor for preeclampsia in a Chinese Han population.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Jun 2019

Xu Longqiang, Li Sai, Liu Zhen, Jiang Shuting, Wang Jingli, Guo Mingzhen, Zhao Xin, Song Weiqing, Liu Shiguo

Abstract excerpt

OBJECTIVE: Previous studies have indicated that the nucleotide-binding domain, leucine-rich repeat containing protein 3 (NLRP3) inflammasome is activated by monosodium urate in the trophoblast of preeclampsia (PE) patients, leading to augmented placental IL-1β levels. Thus, the purpose of our study was to investigate the association between NLRP3 polymorphisms, rs10754558 and rs2027432, and PE in Chinese Han...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Case-Control Studies
Share to NLRP3 gene
Share to NLR Family, Pyrin Domain-Containing 3 Protein
Share to Polymorphism, Single Nucleotide
Share to Pre-Eclampsia
Share to Pregnancy
Share to Young Adult

Source

Identifiers

PMID: 29385859
DOI: 10.1080/14767058.2017.1418313

Genes

NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The NLRP3 rs10754558 polymorphism is a risk factor for preeclampsia in a Chinese Han population.PMID 29385859Read ↗

The NLRP3 Inflammasome Role in the Pathogenesis of Pregnancy Induced Hypertension and PreeclampsiaSemantic proximity Read ↗

NLRP3 inflammasome in peripheral blood monocytes as a risk factor for early onset pre-eclampsiaSemantic proximity Read ↗

Association of NLRP3 and IL-4 VNTR polymorphisms and genetic susceptibility to preeclampsia: A case-control study.Semantic proximity Read ↗

The Association between Polymorphism of NLRP3 rs10754558 and Susceptibility to Arteriosclerosis Obliterans in Chinese Han Male PopulationSemantic proximity Read ↗

Novel association between FOXO3 rs2232365 polymorphism and late-onset preeclampsia: a case-control candidate genetic study.Semantic proximity Read ↗

Placentas from Women with Late-Onset Preeclampsia Exhibit Increased Expression of the NLRP3 Inflammasome MachinerySemantic proximity Read ↗

NLRP1 L155H Polymorphism is a Risk Factor for Preeclampsia Development.Semantic proximity Read ↗

Novel associations of SNPs MYLIP rs3757354 and ABCA1 2230806 gene with early-onset-preeclampsia: A case-control candidate genetic study.Semantic proximity Read ↗

Association and interaction analysis of NLRP3 gene polymorphisms with hypertension risk: A case-control study in ChinaSemantic proximity Read ↗

Role of Toll-Like Receptor 3 Gene Polymorphisms in Preeclampsia.Semantic proximity Read ↗

Genetic variations in IL1A and IL1RN are associated with the risk of preeclampsia in Chinese Han population.Semantic proximity Read ↗

The current role of NLRP3 inflammasome polymorphism in gout susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.