Association and interaction analysis of NLRP3 gene polymorphisms with hypertension risk: A case-control study in China

Abstract excerpt

<title>Abstract</title> <p>Background As an important mechanism for regulating inflammatory reactions, the NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome is considered the central pathogenic link of cardiovascular diseases. This study aimed to analyze the association and interaction between the rs10754558 polymorphism of <italic>NLRP3</italic> and the risk of hypertension among Chinese a...

Topics

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• Blood Pressure
• Case-Control Studies
• China
• East Asian People
• Genetic Association Studies
• Hypertension
• NLR Family, Pyrin Domain-Containing 3 Protein
• Risk Assessment

Identifiers and source

Literature Corpus work

63578c5b-b30f-5f56-97b8-067a0d8df56b

DOI

10.21203/rs.3.rs-3268562/v1