Article
Association and interaction analysis of NLRP3 gene polymorphisms with hypertension risk: a case-control study in China.
BMC cardiovascular disorders - 15 Nov 2024
Xia Wanning, Qi Mingming, Liu Yupeng, Mi Jing, Song Jian, Wu Xuesen
Abstract excerpt
BACKGROUND: The NLRP3 inflammasome, a pivotal mechanism regulating inflammatory responses and featuring the pyrin domain containing 3 (NLRP3) within the NOD-like receptor family, is widely recognized as a central pathogenic factor in cardiovascular diseases. The present study endeavors to delve into the correlation and potential interplay between the rs10754558 polymorphism of NLRP3 and the predisposition to...
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