Article

Genetic associations with ratios between protein levels detect new pQTLs and reveal protein-protein interactions

2023-07-20

Abstract excerpt

Protein quantitative trait loci (pQTLs) are an invaluable source of information for drug target development as they provide genetic evidence to support protein function, suggest relationships between cis - and trans -associated proteins, and link proteins to disease where they collocate with genetic risk loci for clinical endpoints. Using the recently released Olink proteomics data for 1,463 proteins measured in...

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Literature Corpus work: 95efd5dd-41e0-5c6d-885b-1462428e3945
DOI: 10.1101/2023.07.19.549734

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