Article

Proteome-wide Mendelian randomization analyses to identify potential therapeutic targets for lung function and respiratory disease

2025-02-10

Abstract excerpt

<h4>RATIONALE</h4> Impaired lung function predicts mortality and is a diagnostic criterion for chronic obstructive pulmonary disease (COPD). Proteins are often the target of pharmacological interventions, therefore identifying causal links between proteins and lung function could inform understanding of COPD pathophysiology and suggest therapeutic targets. We aim to infer the potential impact of circulating protei...

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Literature Corpus work: f7426a42-b6a2-52ee-9833-58805f177aa1
DOI: 10.1101/2025.02.07.25321860

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