Article

Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma

2020-07-22

Abstract excerpt

<title>Abstract</title> <p>The clinical relevance of immune landscape intratumoural heterogeneity (immune-ITH) and its role in tumour evolution remain largely unexplored. Here, we uncovered significant spatial and phenotypic immune–ITH from multiple tumour sectors and deciphered its relationship with tumour evolution and disease progression in hepatocellular carcinomas (HCC). Immune–ITH was associated with RNA-IT...

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Literature Corpus work: 95ddc08e-dd4f-5c3c-8bb0-4720a19ae5f4
DOI: 10.21203/rs.3.rs-41338/v1

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