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Bulk and single‐cell transcriptome reveal the immuno‐prognostic subtypes and tumour microenvironment heterogeneity in HCC

31 Jan 2024

Abstract excerpt

BACKGROUND & AIMS: Accumulating evidences suggest tumour microenvironment (TME) profoundly influence clinical outcome in hepatocellular carcinoma (HCC). Existing immune subtypes are susceptible to batch effects, and integrative analysis of bulk and single-cell transcriptome is helpful to recognize immune subtypes and TME in HCC. METHODS: Based on the relative expression ordering (REO) of 1259 immune-related...

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PMID: 38293784
DOI: 10.1111/liv.15828

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