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Transcriptome Profiling and Characterization of Peritoneal Metastasis Ovarian Cancer Xenografts in Humanized Mice

2023-10-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Although immunotherapy has not yet been as successful in ovarian cancer (OC), it remains a potential therapeutic strategy. Preclinical models of OC are necessary to evaluate the efficacy of immuno-oncology (IO) drugs targeting human cancer and immune components but have been underutilized. Developing mouse models with a humanized (Hu) immune system can help understand the hu...

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Literature Corpus work
95d87e0c-d4c2-5964-a010-73de8cff0a77
DOI
10.1101/2023.10.27.563867
Open publication

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