Article

HO-3867 mediated modulation of Extracellular vesicles and Tumor microenvironment: A novel immunotherapeutic strategy for ovarian cancer

2025-05-21

Abstract excerpt

<h4>Introduction</h4> Ovarian cancer (OC) remains the most lethal gynecologic malignancy, with poor long-term survival, largely due to its diagnosis at advanced stages and its high rate of recurrence with resistance to platinum therapies. This study evaluates the therapeutic efficacy of HO-3867, a STAT3 inhibitor, and bevacizumab, an anti-VEGF antibody, alone and in combination in an immunocompetent (IC) syngenei...

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Literature Corpus work: 7875c2ba-8842-5c58-bd9d-7c95559baa00
DOI: 10.1101/2025.05.16.653814

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