Article

Epigenome-wide analyses identify DNA methylation signatures of dementia risk

2020-04-11

Abstract excerpt

<h4>INTRODUCTION</h4> Dementia pathogenesis begins years before clinical symptom onset, necessitating the understanding of premorbid risk mechanisms. Here, we investigated potential pathogenic mechanisms by assessing DNA methylation associations with dementia risk factors in Alzheimer’s disease (AD)-free participants. <h4>METHODS</h4> Associations between dementia risk measures (family history, genetic risk score...

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Literature Corpus work: 95b41ca4-1751-5222-a275-e16089e0292e
DOI: 10.1101/2020.04.06.20055517

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