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DNA Methylation Analysis of Candidate Genes Associated with Dementia in Peripheral Blood

1 Dec 2020

Abstract excerpt

Aim: To investigate whether genes implicated in dementia pathogenesis are differently methylated in peripheral blood. Materials & methods: Participants included 160 cognitively healthy individuals aged 70+ years: 73 who were subsequently diagnosed with dementia and 87 controls matched on age, gender, education, smoking and baseline cognition. A total of 49 participants also provided blood samples at diagnosis....

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PMID: 33300824
DOI: 10.2217/epi-2020-0236

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