Article

Intracellular Retention of Estradiol is Mediated by GRAM Domain-Containing Protein ASTER-B in Breast Cancer Cells

2024-05-20

Abstract excerpt

<h4> A bstract </h4> Elevated blood levels of estrogens have been associated with poor prognosis in estrogen receptor-positive (ER+) breast cancers, but the relationship between circulating hormone levels in the blood and intracellular hormone concentrations are not well characterized. We observed that MCF-7 cells treated acutely with 17β-estradiol (E2) retain a substantial amount of the hormone even upon remov...

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Literature Corpus work: 95a28658-d41f-55a4-97c1-43d87a70baf9
DOI: 10.1101/2024.05.16.594581

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Intracellular Retention of Estradiol is Mediated by GRAM Domain-Containing Protein ASTER-B in Breast Cancer CellsDOI 10.1101/2024.05.16.594581Read

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