Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Parametric Mapping for TSPO PET Imaging with Spectral Analysis Impulsive Response Function.

Molecular imaging and biology - 1 Aug 2021

Veronese Mattia, Tuosto Marcello, Marques Tiago Reis, Howes Oliver, Pascual Belen, Yu Meixiang, Masdeu Joseph C, Turkheimer Federico, Bertoldo Alessandra, Zanotti-Fregonara Paolo

Abstract excerpt

PURPOSE: The aim of this study was to investigate the use of spectral analysis (SA) for voxel-wise analysis of TSPO PET imaging studies. TSPO PET quantification is methodologically complicated by the heterogeneity of TSPO expression and its cell-dependent modulation during neuroinflammatory response. Compartmental models to account for this complexity exist, but they are unreliable at the high noise typical of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Carbon Radioisotopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Cross-Sectional Studies

Share to Positron-Emission Tomography

Share to Psychotic Disorders

Share to Purines

Share to Receptors, GABA

Source

Open in PubMed Open full text

Identifiers

PMID: 33475944
DOI: 10.1007/s11307-020-01575-9
PMCID: PMC8277653

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Parametric Mapping for TSPO PET Imaging with Spectral Analysis Impulsive Response Function.PMID 33475944Read ↗

A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET ImagingSemantic proximity Read ↗

Quantification of the Specific Translocator Protein Signal of 18F-PBR111 in Healthy Humans: A Genetic Polymorphism Effect on In Vivo BindingSemantic proximity Read ↗

[18F]VUIIS1009B Features a Superior Imaging Performance to [18F]DPA-714 in TSPO Density Characterization for Neuroinflammatory PET ImagingSemantic proximity Read ↗

Quantitative imaging of neuroinflammation in human white matter: a positron emission tomography study with translocator protein 18 kDa radioligand, [18F]-FEPPA.Semantic proximity Read ↗

Translocator Protein (18 kDa) Polymorphism (rs6971) Explains <i>in-vivo</i> Brain Binding Affinity of the PET Radioligand [ <sup>18</sup> F]-FEPPASemantic proximity Read ↗

Feasibility study of TSPO quantification with [18F]FEPPA using population-based input function.Semantic proximity Read ↗

Optimized Quantification of Translocator Protein Radioligand ¹⁸F-DPA-714 Uptake in the Brain of Genotyped Healthy Volunteers.Semantic proximity Read ↗

The Low-Affinity Binding of Second Generation Radiotracers Targeting TSPO is Associated with a Unique Allosteric Binding Site.Semantic proximity Read ↗

Network-based disease fingerprinting with neuroinflammation PET imagingSemantic proximity Read ↗

Peripheral inflammation is associated with reduced influx of TSPO PET tracers into the brain: insights from a non-invasive mapping methodologySemantic proximity Read ↗

Peripheral inflammation is associated with reduced influx of TSPO PET tracers into the brain: insights from a non-invasive mapping methodologySemantic proximity Read ↗

Test-retest reproducibility of [(11)C]PBR28 binding to TSPO in healthy control subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.