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Article

Variants in the <i>DDX6-CXCR5</i> autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

2023-10-06

Abstract excerpt

<h4>ABSTRACT</h4> Fine mapping and bioinformatic analysis of the DDX6-CXCR5 genetic risk association in Sjögren’s Disease (SjD) and Systemic Lupus Erythematosus (SLE) identified five common SNPs with functional evidence in immune cell types: rs4938573, rs57494551, rs4938572, rs4936443, rs7117261. Functional interrogation of nuclear protein binding affinity, enhancer/promoter regulatory activity, and chromatin-ch...

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Literature Corpus work
953f3e6a-a4b1-56d1-9228-11f09e29f0be
DOI
10.1101/2023.10.05.561076
Open publication

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Variants in the <i>DDX6-CXCR5</i> autoimmune disease risk locus influence the regulatory network in immune cells and salivary glandDOI 10.1101/2023.10.05.561076
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