Article

Hematological alterations associated with the SNV rs10974944, part of the 46/1 haplotype, in patients from the Brazilian Amazon with BCR::ABL1-negative myeloproliferative neoplasms

2024-02-02

Abstract excerpt

BCR::ABL1-negative myeloproliferative neoplasms are hematopoietic disorders characterized by panmyelosis. JAK2 V617F is a frequent variant in these diseases and often occurs in the 46/1 haplotype. The G allele of rs10974944 has been shown to be associated with this variant, specifically its acquisition, correlations with familial cases, and laboratory alterations. This study evaluated the association between the 4...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 94d59ada-efd8-5b61-ab3f-74725bc9bd42
DOI: 10.21203/rs.3.rs-3880113/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hematological alterations associated with the SNV rs10974944, part of the 46/1 haplotype, in patients from the Brazilian Amazon with BCR::ABL1-negative myeloproliferative neoplasmsDOI 10.21203/rs.3.rs-3880113/v1Read

Exploring hematological alterations and genetics linked to SNV rs10974944 in myeloproliferative neoplasms among Amazon patients.Semantic proximity Read

JAK2 46/1 haplotype is associated with JAK2 V617F--positive myeloproliferative neoplasms in Brazilian patients.Semantic proximity Read

The G allele of the JAK2 rs10974944 SNP, part of JAK2 46/1 haplotype, is strongly associated with JAK2 V617F-positive myeloproliferative neoplasms.Semantic proximity Read

JAK2 46/1 (GGCC) Haplotype: A Biomarker for Oncogenesis, Risk Stratification, and Drug Resistance in Myeloproliferative NeoplasmsSemantic proximity Read

The Contribution of JAK2 46/1 Haplotype in the Predisposition to Myeloproliferative Neoplasms.Semantic proximity Read

Association of JAK2 Haplotype GGCC_46/1 with the Response to Onco-Drug in MPNs Patients Positive for JAK2V617F MutationSemantic proximity Read

JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms.Semantic proximity Read

Evaluation of the association between the JAK2 46/1 haplotype and chronic myeloproliferative neoplasms in a Brazilian population.Semantic proximity Read

The JAK2 GGCC (46/1) Haplotype in Myeloproliferative Neoplasms: Causal or Random?Semantic proximity Read

The JAK2 46/1 haplotype in Budd-Chiari syndrome and portal vein thrombosis.Semantic proximity Read

JAK2 46/1 haplotype is associated with JAK2 V617F-positive myeloproliferative neoplasms in Japanese patients.Semantic proximity Read

The C allele of JAK2 rs4495487 is an additional candidate locus that contributes to myeloproliferative neoplasm predisposition in the Japanese population.Semantic proximity Read