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JAK2 46/1 (GGCC) Haplotype: A Biomarker for Oncogenesis, Risk Stratification, and Drug Resistance in Myeloproliferative Neoplasms

2025-09-09

Abstract excerpt

<h4>Background: </h4> The JAK2 46/1 (&quot;GGCC&quot;) haplotype, is an inherited genetic variation within the JAK2 gene locus that has become a focal point in research related to oncogenesis, particularly in myeloproliferative neoplasms (MPNs). <h4>Methods:</h4> We conducted a narrative review of landmark discoveries in hematological malignancies and JAK2, focusing its role on oncogenesis, risk stratification, an...

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Literature Corpus work
6f794188-9f56-5c77-abf6-9d3d547e57ee
DOI
10.20944/preprints202509.0801.v1
Open publication

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JAK2 46/1 (GGCC) Haplotype: A Biomarker for Oncogenesis, Risk Stratification, and Drug Resistance in Myeloproliferative NeoplasmsDOI 10.20944/preprints202509.0801.v1
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