JAK2 46/1 haplotype is associated with JAK2 V617F--positive myeloproliferative neoplasms in Brazilian patients.

doi:10.1111/ijlh.12380

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Article

JAK2 46/1 haplotype is associated with JAK2 V617F--positive myeloproliferative neoplasms in Brazilian patients.

International journal of laboratory hematology - 1 Oct 2015

Macedo L C, Santos B C, Pagliarini-e-Silva S, Pagnano K B B, Rodrigues C, Quintero F C, Ferreira M E, Baraldi E C, Ambrosio-Albuquerque E P, Sell A M, Visentainer J E L

Abstract excerpt

INTRODUCTION: This study aimed to verify the association between the JAK2 46/1 haplotype (V617F positive) and some hematological parameters in BCR-ABL-negative chronic myeloproliferative neoplasms (cMPNs) in our population. METHODS: The blood samples obtained from the patients with cMPN were genotyped for the JAK2 V617F mutation and JAK2 rs10974944 SNP screening using a PCR-RFLP assay. RESULTS: The JAK2 V617F...

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PMID: 25959311
DOI: 10.1111/ijlh.12380

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JAK2
BCR

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