Article

Liquidity of gene co-expression trajectories across the lifespan highlights delayed maturation and the perinatal GABA switch in schizophrenia risk

2026-06-11

Abstract excerpt

Schizophrenia genetic and environmental risk factors play out largely in early life, biasing development toward a pathogenic trajectory that becomes clinically apparent in early adulthood, when the disorder typically onsets. Here, we convert snapshots of gene expression in postmortem brain at a moment in time into a dynamic lifetime series employing the “liquidity” metric, a novel tool to track the evolution of ne...

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Literature Corpus work: 9497c31c-ce25-5fc4-ba6b-d99e12ee6a33
DOI: 10.64898/2026.06.10.731457

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