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Article

Schizophrenia Genomics: Convergence on Synaptic Development, Adult Synaptic Plasticity, or Both?

Biological psychiatry - 15 Apr 2022

Hall Jeremy, Bray Nicholas J

Abstract excerpt

Large-scale genomic studies of schizophrenia have identified hundreds of genetic loci conferring risk to the disorder. This progress offers an important route toward defining the biological basis of the condition and potentially developing new treatments. In this review, we discuss insights from recent genome-wide association study, copy number variant, and exome sequencing analyses of schizophrenia, together...

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Identifiers

PMID: 34974922
DOI: 10.1016/j.biopsych.2021.10.018
PMCID: PMC8929434

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