Article
The Genesis of Schizophrenia: An Origin Story.
The American journal of psychiatry - 1 Jun 2024
Birnbaum Rebecca, Weinberger Daniel R
Abstract excerpt
Schizophrenia is routinely referred to as a neurodevelopmental disorder, but the role of brain development in a disorder typically diagnosed during early adult life is enigmatic. The authors revisit the neurodevelopmental model of schizophrenia with genomic insights from the most recent schizophrenia clinical genetic association studies, transcriptomic and epigenomic analyses from human postmortem brain studies,...
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