Article

Distinct brain atrophy progression subtypes underlie phenoconversion in isolated REM sleep behaviour disorder

2024-09-06

Abstract excerpt

<h4>Background</h4> Synucleinopathies manifest as a spectrum of disorders that vary in features and severity, including idiopathic/isolated REM sleep behaviour disorder (iRBD) and dementia with Lewy bodies. Patterns of brain atrophy in iRBD are already reminiscent of what is later seen in overt disease and are related to cognitive impairment, being associated with the development of dementia with Lewy bodies. Howe...

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Literature Corpus work: 9442c0ba-c1b6-54f1-b259-5553cc900e5c
DOI: 10.1101/2024.09.05.24313131

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