Article

Toxicogenomic identification of repositioned therapy for a monogenic disease

2019-09-23

Abstract excerpt

The cost of drug development from initial concept to FDA approval has been estimated to be about 2.6 billion USD. 1 This cost precludes development of targeted therapies for rare diseases such as monogenetic cardiomyopathies. As part of the Library of Integrated Network-based Cellular Signatures (LINCS) program funded by the NIH, the Broad Institute of MIT has publicly released transcriptional profiles quantifyin...

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Literature Corpus work: 94090410-1af7-5236-9d46-abf1839a5ebf
DOI: 10.1101/748863

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