Article

Personalized transcriptome signatures in a cardiomyopathy stem cell biobank

2024-05-14

Abstract excerpt

<h4>BACKGROUND</h4> There is growing evidence that pathogenic mutations do not fully explain hypertrophic (HCM) or dilated (DCM) cardiomyopathy phenotypes. We hypothesized that if a patient’s genetic background was influencing cardiomyopathy this should be detectable as signatures in gene expression. We built a cardiomyopathy biobank resource for interrogating personalized genotype phenotype relationships in huma...

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Literature Corpus work: 6f32ac79-1cb8-504e-8634-44cccc161ae0
DOI: 10.1101/2024.05.10.593618

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