Article

Predicting protein targets for drug-like compounds using transcriptomics

2018-01-25

Abstract excerpt

The development of an expanded chemical space for screening is an essential step in the challenge of identifying chemical probes for new, genomic-era protein targets. However, the difficulty of identifying targets for novel compounds leads to the prioritization of synthesis linked to known active scaffolds that bind familiar protein families, slowing the exploration of available chemical space. To change this para...

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Literature Corpus work: 2765fc51-b8b0-500c-8072-f7ccc4b066d3
DOI: 10.1101/254367

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