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Article

Constitutive Androstane Receptor contributes towards increased drug clearance in cholestasis

2019-01-15

Abstract excerpt

Understanding the alterations in drug metabolism in different liver diseases is crucial for appropriate therapeutic intervention. We performed high-throughput RNA sequencing on various liver injury models, including cholestasis, diet-induced steatosis, and regeneration. Comparative liver transcriptome analysis revealed overlapping and distinct gene profiles among different liver diseases. Particularly, cholestatic...

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Literature Corpus work
93ee6119-e2d5-5256-931e-99c7ab4c47d5
DOI
10.1101/520692
Open publication

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Constitutive Androstane Receptor contributes towards increased drug clearance in cholestasisDOI 10.1101/520692
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