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Transcriptomic profiling of hepatic tissues for drug metabolism genes in nonalcoholic fatty liver disease: A study of human and animals

4 Jan 2023

Abstract excerpt

Background Drug metabolism genes are involved in the in vivo metabolic processing of drugs. In previous research, we found that a high-fat diet affected the transcript levels of mouse hepatic genes responsible for drug metabolism. Aims Our research intends to discover the drug metabolism genes that are dysregulated at the transcriptome level in nonalcoholic fatty liver disease (NAFLD). Methods We analyzed the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36686439
DOI: 10.3389/fendo.2022.1034494

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