Article
Identification and functional analyses of 11,769 full-length human cDNAs focused on alternative splicing.
DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Dec 2009
Wakamatsu Ai, Kimura Kouichi, Yamamoto Jun-Ichi, Nishikawa Tetsuo, Nomura Nobuo, Sugano Sumio, Isogai Takao
Abstract excerpt
We analyzed diversity of mRNA produced as a result of alternative splicing in order to evaluate gene function. First, we predicted the number of human genes transcribed into protein-coding mRNAs by using the sequence information of full-length cDNAs and 5'-ESTs and obtained 23 241 of such human genes. Next, using these genes, we analyzed the mRNA diversity and consequently sequenced and identified 11 769 human...
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