Article

Integrating Molecular Analyses with the 2021 WHO Classification for a More Precise Diagnosis of Adult Pilocytic Astrocytomas

2024-08-19

Abstract excerpt

<title>Abstract</title> <p>Pilocytic astrocytoma (PA) is a benign grade 1 glioma according to the World Health Organization (WHO). It is frequent in pediatric population, but very rare in adults, where it can be associated with worse prognosis. Molecular features of pediatric PA are associated with dysregulation of the MAPK pathway, most often showing BRAF alterations such as the <italic>KIAA1549::BRAF</italic> (...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 93c8ed42-c34c-5980-b27b-517a58239211
DOI: 10.21203/rs.3.rs-4762490/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Integrating Molecular Analyses with the 2021 WHO Classification for a More Precise Diagnosis of Adult Pilocytic AstrocytomasDOI 10.21203/rs.3.rs-4762490/v1Read

Adult pilocytic astrocytoma in the molecular era: a comprehensive reviewSemantic proximity Read

High-Grade Astrocytoma With Piloid Features: An Aggressive Clinicogenomic Entity Distinct From Pilocytic Astrocytoma.Semantic proximity Read

Pediatric High-Grade Astrocytoma With Piloid Features: A Comprehensive Literature Review.Semantic proximity Read

The histomolecular criteria established for adult anaplastic pilocytic astrocytoma are not applicable to the pediatric populationSemantic proximity Read

[Pay attention to molecular pathological diagnosis of pediatric glioma].Semantic proximity Read

Integrated genetic profiling of archival pediatric high-grade glial tumors and reassessment with 2021 WHO classification of paediatric CNS tumours.Semantic proximity Read

Molecular alterations in the integrated diagnosis of pediatric glial and glioneuronal tumors: A single center experience.Semantic proximity Read

Unraveling morphology, methylation profiling, and diagnostic challenges in BRAF-Mutant pediatric glial and glioneuronal tumors.Semantic proximity Read

The importance of escalating molecular diagnostics in patients with low-grade pediatric brain cancer.Semantic proximity Read

Spectrum of qualitative and quantitative imaging of pilomyxoid, intermediate pilomyxoid and pilocytic astrocytomas in relation to their genetic alterations.Semantic proximity Read

[Evolution of Glioma Diagnosis: The WHO 2021 Classification and Beyond].Semantic proximity Read

Pilocytic astrocytoma harboring a novel GNAI3-BRAF fusion.Semantic proximity Read