Article
Molecular alterations in the integrated diagnosis of pediatric glial and glioneuronal tumors: A single center experience.
PloS one - 1 Jan 2022
Colli Sandra Lorena, Cardoso Nazarena, Massone Carla Antonella, Cores María, García Lombardi Mercedes, De Matteo Elena Noemí, Lorenzetti Mario Alejandro, Preciado María Victoria
Abstract excerpt
OBJECTIVES: Tumors of the central nervous system (CNS) are the most common pediatric solid tumors, where low grade (LGG) and high grade gliomas (HGG) represent up to 55% of CNS tumors. Current molecular classification of these tumors results in a more accurate diagnosis and risk stratification, which ultimately enables individualized treatment strategies. Identifying known alterations is a suitable approach,...
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