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Ratiometric Fluorescent Protein Biosensors Reveal Citrate Dynamics and Cellular Heterogeneity

2026-04-20

Abstract excerpt

Citrate is a central intermediate metabolite linking the tricarboxylic acid cycle and lipid biosynthesis. Tools for monitoring of spatiotemporal citrate dynamics are critical for getting a better understanding of cellular metabolism. Here, we develope genetically encoded excitation ratiometric biosensors for citrate, based on our previous intensiometric green fluorescence protein-based citrate biosensor, Citron1....

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Literature Corpus work
93c3cf38-a8b4-52a2-94f2-eb95b432a627
DOI
10.64898/2026.04.16.718871
Open publication

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Ratiometric Fluorescent Protein Biosensors Reveal Citrate Dynamics and Cellular HeterogeneityDOI 10.64898/2026.04.16.718871
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