Article
Bright luminescence of Vibrio fischeri aconitase mutants reveals a connection between citrate and the Gac/Csr regulatory system.
Molecular microbiology - 1 Jan 2015
Septer Alecia N, Bose Jeffrey L, Lipzen Anna, Martin Joel, Whistler Cheryl, Stabb Eric V
Abstract excerpt
The Gac/Csr regulatory system is conserved throughout the γ-proteobacteria and controls key pathways in central carbon metabolism, quorum sensing, biofilm formation and virulence in important plant and animal pathogens. Here we show that elevated intracellular citrate levels in a Vibrio fischeri aconitase mutant correlate with activation of the Gac/Csr cascade and induction of bright luminescence. Spontaneous or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.