Article

Activation of the <i>Androgen Receptor</i> gene by BORIS/CTCFL in prostate cancer cells

2017-09-29

Abstract excerpt

BORIS/CTCFL, a paralogue of the chromatin architectural protein CTCF, is a member of the cancer-testis antigen family, normally present in the testes. BORIS is expressed in various tumours, including prostate cancers, however the function of BORIS in cancer cells is not well defined. The androgen receptor (AR) plays a critical role in the normal development of a human prostate gland and pathogenesis of prostate ca...

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Literature Corpus work: 93b81b30-347c-5264-b05f-76f57f206d68
DOI: 10.1101/195875

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