Article

Brain-first forms of Parkinson’s Disease are over-represented in patients with non-responsive resting tremor

2024-07-24

Abstract excerpt

Motor subtypes in Parkinson’s Disease (PD) are unstable over time, limiting mechanistic insights and biomarker discovery. We focused on Rest Tremor (RT) as a symptom to test for phenotype stability and link them to specific circuits and disease mechanisms. Using the PPMI cohort data over 5 years we found that RT we found that RT is more stable than common Tremor-Dominant definitions, a stability also seen for ther...

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Literature Corpus work: 6d02401d-97c1-5c44-b26a-4bd5bbd980b3
DOI: 10.1101/2024.07.23.24310859

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