Article

Trapping DNA-radicals with DMPO reduced hypochlorous acid-induced 8-oxo-7,8-dihydro-2’-deoxyguanosine and mutagenesis in lung epithelial cells

2024-06-20

Abstract excerpt

<h4>ABSTRACT</h4> Irritation causes the recruitment and activation of neutrophils in the stressed airways. This process is known as neutrophilic inflammation. This process results in myeloperoxidase (MPO), an enzyme contained inside neutrophil azurophilic granules, being released as neutrophil extracellular traps (NETs), which also contain genomic DNA, modified histones, and other proteins. In the airways, releas...

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Literature Corpus work: 938a6f8b-e355-5fb7-a928-673d4fed187f
DOI: 10.1101/2024.06.18.599657

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Trapping DNA-radicals with DMPO reduced hypochlorous acid-induced 8-oxo-7,8-dihydro-2’-deoxyguanosine and mutagenesis in lung epithelial cellsDOI 10.1101/2024.06.18.599657Read

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